It is unbelievable that the principle of formaldehyde poisoning the human body is the same as that of processed corpse specimens
Formaldehyde is a highly reactive small molecule organic compound that is volatile as a gas at room temperature. It also has a strong pungent odor and is easily distinguish. How toxic is formaldehyde? Zhu Dunru made a comparison using methanol and formic acid, which are equally toxic. After the oxidation of methanol, formaldehyde can be obtained, and after formaldehyde is continuously oxidized, formic acid can be obtained. All three are toxic substances. At the same dose, the toxicity ratio to the human body is methanol: formaldehyde: formic acid =:: that is, the toxicity of formic acid is six times that of methanol and the toxicity of formaldehyde is thirty times that of methanol. Formaldehyde is often made into an aqueous solution with a concentration of %-%. The % aqueous solution is also called formalin, which is a solution that everyone knows is used to preserve corpse specimens and sterilize and disinfect. The harm of formaldehyde to the human body is the same as the principle of formalin preserving corpses.
Formaldehyde has high reactivity and can undergo nucleophilic addition reactions with molecules with hydroxyl, mercapto, and amino groups. Finally, formaldehyde, as a methylene donor, reacts with two of the above groups. The free molecular chains are cross-linked by formaldehyde and lose their original physiological functions. There are a large number of hydroxyl groups, sulfhydryl groups, and amino groups in the human body's cells and enzyme systems. When exposed to formaldehyde, they will react to produce cytotoxicity and denature proteins. In other words, formaldehyde will prevent the synthesis of nuclear proteins in the human body, inhibit cell division, and inhibit the synthesis of nuclei and cytoplasm. Formalin solution uses this function of formaldehyde to effectively kill bacterial propagules and prevent the corpse from decaying.
What are the reactions after people are poisoned by formaldehyde?
For the human body, formaldehyde initially irritates the eye mucosa at low concentrations. At slightly higher concentrations, it irritates the upper respiratory tract, causing coughing, chest tightness, and a special feeling on the forehead. The pressure can cause mucous membrane ulceration and cause inflammation in the lungs. The most sensitive among them is the sense of smell and stimulation, so its main harm is the irritation of mucous membranes. Formaldehyde is easily absorbed through the respiratory tract. % of formaldehyde inhaled through the nose remains in the nasal tissue. When inhaled at high concentrations, severe respiratory tract irritation and edema will occur, respiratory resistance will increase, breathing frequency will decrease, eye irritation, and headaches will occur. According to reports, when the formaldehyde content in the air reaches .~.mg/cubic meter, you can smell up to .~.mg/cubic meter and have a stinging sensation in the eyes and reach .~.mg/cubic meter and have an irritation in the throat. mg/cubic meter, people will shed tears within minutes if exposed to it; mg/cubic meter, intense tears will occur if exposed to it for hours; mg/cubic meter, edema, inflammation, and pneumonia will occur; mg/cubic meter, people will die.
Repeated inhalation of small doses of formaldehyde in the human body can induce allergic reactions and asthma. Direct skin contact with formaldehyde can cause allergic dermatitis, stains, and necrosis. In vitro test results of various mammalian cells have shown that formaldehyde can induce gene mutations in mammalian cells and has a damaging effect on D. In experiments, animals exposed to high concentrations of inhaled poison can cause nasal squamous cell carcinoma. Population epidemiological surveys have shown that exposure to formaldehyde increases the risk of nasal, nasopharyngeal and oral cancer.
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Shouguang Formaldehyde Removal: How formaldehyde harms our body